Will my car need a new head unit and speakers?

My sister gave me her PPI 600 watt amp. It has 6 channels (not exactly sure what this means). I also received a sub that is a 12" Kicker in a box. I drive a 2007 Honda Civic Hybrid with a stock touch screen navigation system. I have no idea how wiring a new sound system works. Will I need a new head unit? I don't think I can do that because there's a nav system. Will I need new speakers to accompany this new power? Pretty sure the speakers I have right now are super weak. How much would new speakers cost? I'm so lost. I appreciate any help! Thank you.

Added (1). I'd also like to add that I would have this sound system installed somewhere. I would not do it myself. I'm just wondering what I'm dealing with here.

Take the car and the equipment your sister gave you to a shop and see what they think (get a quote before they do anything).

You can install an amp w/o changing the stock head unit.
The issue is getting signal from the radio to the amp. IF the amp has high (speaker) level inputs you can do this by connecting (piggy-backing) speaker wires off the existing stock speaker wires which will then be connected to the amp's speaker level inputs.
If the amp doesn't have high/speaker level inputs you'd need to add a line output converter which connects in a similar fashion to the stock speaker wires, but it provides RCA outputs to connect to the amp.

The stock speakers may not be able to withstand the power of the amp, but we would need to know what model amp it is to make a reasonable speculation.

A decent pair of replacement speakers can usually be found in the $50 range.

The amp would need to be wired for power as well -- power, ground, remote turn-on, and the could be a little work involved to get speaker wires connected between the amp and speakers.

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