Why is my 2005 Honda CRV not holding Frion?

I've replaced the compressor, the clutch, the belts, the hoses, and the dual fans, but it still won't hold Frion for more than 2 weeks. If I'm lucky, it will sometimes work afterwards if I drive over 40 mph.

This is a compressor issue that Honda refuses to acknowledge. Everybody who bought a CRV is basically screwed in the AC department. As amazing as Honda's products are (I'm a Honda motorcycle nut), their service departments are the very worst in the world for customer service and satisfaction. They simply don't care. At all.

http://repairpal.com/air-conditioning-is-blowing-warm-air-497

Check your Schrader valves in your high/low

You should take it to a professional and have them leak test and locate the leak instead of throwing parts at it. That way you know exactly what the problem is and address that problem.