I have a 2003 Honda Oddessy it makes a whine noise only when I accelerate. If I let off the gas it stops and goes away. What could it?

I have a 2003 Honda Oddessy it makes a while noise only when I accelerate. If I let off the gas it stops and goes away. What could it possibly be? Sounds like it's coming from the driver side for sure.

'Sounds' like a U joint in the front drive. When the transmission shifts to a higher gear, does the whine also change or not? Might need a 'new' half-shaft, which is not that big of a deal anymore.

Its probably the engine

Wheel bearing?

Check the transmission fluid.

Power steering pump. Check that level.

Put it in Neutral or Park and step on the gas while standing still and listen to hear if it makes the same sound. That is to separate engine noise from transmission or wheel noise.
Otherwise see a mechanic and let them hear it. They probably can hear it while on their coffee break.