Is it possible to upgrade Honda Pilot 2005 Radio & Navigation system?

I love that car. But it's coming to the time where We don't use cassette and CD anymore. All those annoying buttons are there for no reason. There's many space for Aux and Blutooth now.

Just wondering if it is possible to upgrade the entire system to a more modern gadgets. I want to pull out the navigation screen, radio, Cassette and DVD player out and just simply replace it with a more modern system.

Is this possible? I think you understand what I mean… If it is possible, Please help me find some parts online and share links.

My car is a 2005 Honda Pilot EX
Currently have a backup cam that is so outdated, it's blurry. I d like to upgrade that camera too if possible.

Yes, it IS possible to REPLACE your factory stereo with a new one. Go talk to people at a local audio shop.

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I need the manual transmission flued chart. Any help is highly appreciated!