Cylinder 2 misfire 2014 Honda Civic?

Suddenly lost power on my car a few days back. Began accelerating very slowly. Check engine light came on. Ran diagnostic that read cylinder 2 misfire. I figured it was spark plugs since I have been on my original part for 118k miles. Replaced them, cleared my check engine light, and the car ran fine for 5-10 seconds then the same problem happened again. I'm figuring the next step would be replacing the ignition coil to see if that does the trick. Looking for advice first.

Could be a bad electrical connection at the fuel injector.

I believe it has separate coils, swap the #2 & #3 and see what happens. If that doesn't do it, swap injectors.Troubleshooting can be done without spending money.

Pilsner Man is correct. There's one coil for each cylinder on the vehicle. By swapping the coils, you can identify a bad coil if the misfire moves from one cylinder to another, however if the misfire remains in the same position, try doing a resistance check on the corresponding injector. You'll need to figure out the exact ohm specification for your injectors as I don't know them off hand. It should only read so many ohms if the injector is good. If you get infinite resistance, the injector is internally open and will need to be replaced.

All Honda's need their valves adjusted every 60,000 miles. Only use NGK or Denso brand spark plugs!

First swap that coil to a different cylinder and see if the misfire goes along with it, confirming the coil is the problem.

Take it to a certified mechanic the has the proper equipment to diagnose the problem.

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