Which car brand is the most dependable?

A. Toyota
B. Lexus
C. Honda

Lexus is the luxury vehicle division of Japanese automaker Toyota.
You wouldn't go wrong picking any of those you mentioned.
I have a Toyota and it's been the best car of all the ones I've owned.

Depends on how much you're looking to spend.

Well, Lexus is nothing more than a pimped out, over priced Toyota, so they're the same. Still, I also believe they're slightly more dependable than Honda, but only slightly.

Toyota.

Honda.